EFFECTS OF DIAZEPAM ON SWIMMING PERFORMANCE, BODY WEIGHT AND SOME HEMATOLOGICAL PARAMETERS OF CARP, CYPRINUS CARPIO.

EFFECTS OF DIAZEPAM ON SWIMMING PERFORMANCE, BODY

WEIGHT AND SOME HEMATOLOGICAL PARAMETERS OF CARP,

CYPRINUS CARPIO.
BY
M.H. MOURAD·, and B. KLYSZEJKO
·National Institute of Oceanography & Fishe.”ies, Alexandria, Egypt.
Key Words: Diazepam, Physiological responses, Cyprinus carpio.
ABSTRACT
Ihe e.Uects ofdiazepam on swimming performance, body weight and some
hematological parameters ofCalp hal’e been investigated Fish exposed to
d(fferent concentrations (?( diazepam resulted in decreasing of the mean
jlvimming .~peed\· significantly. An improvement in slvimming time, fish travel
and physical e.{(ort were obserl’ed after exposure to 0.05 and 0.10 mg/l
diazepam. In contrast, a rise (?f diazepam concentration to 0.50 mg/l resulted
in the decrease ~f swimming pe/jormance. It was found that diazepam at
concentrations (l 0.05 and 0.10 mg/l had a good effect on the coefficients
connected with gas exchange as well as the parameters connected with
acid-base and ionic equilibrium. An increase in the levels ofcholesterol and
fibrinogen were alm detected after diazepam treatment while the level of
glucose was decreased A sign(ficant increase in body weight was also
observed The possibilities (l the pharmacological effects ofdiazepam are
discussed